A Revolutionary Treatment for Peripheral Artery Disease (PAD)

The Alucent NVS Vessel Restoration System is designed to create a natural, stent-like scaffold using the body’s own tissue and processes. An all-in-one, integrated procedural system, Alucent NVS combines standard angioplasty techniques with photoactivated extracellular matrix protein linking.

Designed to provide durable vessel patency, Alucent NVS has the potential to transform the way vascular disease is treated and improve long-term clinical outcomes in the treatment of PAD.

Greater than 60% failure rate of balloon angioplasty after 12 months 1

Studies have shown that balloon angioplasty and stenting have high failure rates and complications such as restenosis occur after only a year or two in patients with PAD. In contrast, Alucent NVS is designed to provide durable vessel patency by creating a stent-like, natural scaffold in the vessel wall – eliminating the risk of complications specific to conventional stents and other implants. In preclinical studies, Alucent NVS has demonstrated the ability to expand the diameter of a blood vessel, without impacting the vessel’s native flexibility and function.

A Revolutionary Treatment for Peripheral Artery Disease (PAD)

How It Works


Standard balloon angioplasty is performed to pre-treat the vessel.

Small Molecule Compound Delivery

The NVS photoactivable small molecule compound is delivered to the diseased arterial wall, where it quickly penetrates into and through the arterial wall.

Light Activation

The NVS light fiber is activated. The light source photoactivates the small molecule compound that has permeated into the arterial tissues, creating durable linking within the vessel’s native connective tissue.


The natural scaffold is created and the vessel lumen is restored. The balloon and catheter are removed and standard interventional methods are followed to finalize the procedure.